Niacinamide Is the Brightening, Clearing Ingredient Derms Want You to Use

Niacinamide—aka vitamin B3—is one of those ingredients you can find in almost any type of skincare product—be it a serum, moisturizer, or cleanser. Perhaps you've seen the viral TikTok reviews of dermatologists singing its praises, or perhaps you've seen it on the ingredient labels of cult-favorite products (like the Peach & Lily Glass Skin Refining Serum or Glow Recipe's Watermelon Niacinamide Dew Drops).

So what exactly does niacinamide do? This superstar ingredient has dermatologists' seal of approval for everything from brightening, to clearing the skin, and even reducing fine lines and wrinkles. Curious about the benefits and how to use niacinamide in your personal skincare routine? Ahead, two board-certified dermatologists explain everything you need to know about niacinamide.

Keep reading to find out what makes vitamin B3 tick regarding its under-the-radar skin benefits.

What Is Niacinamide?

"When we think about the skin benefits of niacinamide, we're referring to a specific form of B3 (an amide) called nicotinamide [also known as niacinamide]. Nicotinamide is an essential water-soluble vitamin, which is not synthesized in the body, meaning we have to eat it to receive its benefits," says Herrmann. Additionally, the vitamin has been incorporated into skincare products since—as Herrmann stated—our bodies don't produce it on their own. Therefore, if we want to reap the brightening benefits of nicotinamide, it needs to be ingested via supplement or applied topically to the skin: "Nicotinamide is in some topical formulations and can be used in the morning or night as a cream, typically after gentle cleansing." Vitamin B3 can also be found in some of Byrdie HQ's favorite serums (see below), which can either be applied prior to or into your go-to night cream.

After three months of niacinamide use, Byrdie editor Holly Rhue's skin is calmer and brighter.

The Benefits of Niacinamide

In short, it's incredibly restorative. "Nicotinamide helps restore cellular energy, repair damaged DNA, and reduce the immunosuppressive effects of sun-induced UV rays." With a fountain of youth likeness, Herrmann compares vitamin B3 to that of a "well-oiled machine," fighting off internal and external stressors that can ultimately lead to the deterioration or breakdown of our skin and premature signs of aging like discoloration and wrinkles.

Concerning brightness specifically, she tells us: "Nicotinamide has been shown to prevent the transfer of pigment within the skin, which can help reduce brown spots." Less redness (thanks to vitamin B3's anti-inflammatory properties), preserved hydration, a strengthened skin barrier, and the improved synthesis of healthy fats (key for glowing skin) are other benefits cited by Herrmann.

"I recommend it for my sensitive skin patients, or those with other conditions such as rosacea or eczema," Nazarian tells us. "It can also be found in sunscreens, such as Elta MD UV Clear, and is a good option for people who are concerned about irritation from their skincare products or have difficulty using creams due to allergies. The oral version can also be used to treat acne—and is great when oral medications such as antibiotics aren’t well tolerated."

Can You Use Niacinamide With Other Active Ingredients?

Another lesser-known fact is that most skincare products work better when paired with other ingredients. "Concerning pigmentation specifically, nicotinamide is best paired with other ingredients like hydroquinone, kojic acid, arbutin, and soy, which can work synergistically on the 'pigment pathway' to best help clear brown spots and discoloration," says Herrmann. 

Nicotinamide/Niacinimide vs. Nicotinic Acid

However, here is one common misconception when it comes to B3 and its (multiple) monikers: "Nicotinamide is a specific amide (a particular chemical structure) form of B3. It's not niacin, the acid form of this vitamin. Niacin is much more easily found at the drugstore but [occasionally] has the unpleasant side effect of flushing that nicotinamide doesn't have." Not into a red face? Make sure to scan your ingredient lists, and don't assume that despite the lack of "-amide" it's still the same ingredient.

Potential Side Effects

"Niacinamide is a powerful ingredient for both skin moisturization and skin brightening," Mun reiterates. "But when used in high concentrations in a skincare formulation, it may cause skin irritation. So, it is recommended to use low concentrations (1-2 percent) of vitamin B3 in a formulation." Basically, don't overuse, or you might experience some redness or (even worse) dermatitis.

How To Use It

The key to reaping vitamin B3s benefits comes down to choosing your product selection wisely. Herrmann explains that our skin is smart and since its job is to act as a barrier—protecting our bodies from potentially harmful invaders—not all topical formulations may boast the technology to effectively penetrate.

"Any topically applied active ingredient must be formulated in a way so that it can get into the skin to where it's needed," she says. "If nicotinamide successfully penetrates this barrier, it can be effective." Look for B3 products with scientific studies to back them up and not just appealing ingredient lists. You should use it in the morning, and it'll likely be contained in products that boast brightening properties.